Rekombinanter ZEB1 Antikörper (AA 750-800)

Produktnummer ABIN7455173

Dieser Anti-ZEB1 Antikörper ist ein Kaninchen Monoklonal Antikörper zur Detektion von ZEB1 in IHC, ICC, FACS und IP. Geeignet für Human und Maus.

Kurzübersicht für Rekombinanter ZEB1 Antikörper (AA 750-800) (ABIN7455173)

Target: ZEB1 (Zinc Finger E-Box Binding Homeobox 1 (ZEB1))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser ZEB1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunoprecipitation (IP)

Klon: BLR217K

Produktdetails anti-ZEB1 Antikörper

Bindungsspezifität: AA 750-800

Verwendungszweck: Rabbit anti-ZEB1 Recombinant Monoclonal Antibody [BLR217K]

Aufreinigung: Purified

Immunogen: between AA 750 and 800

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IHC: 1:100 to 1:500. Epitope retrieval with citrate Buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 6 μL/1 mg lysate

ICC: 1:100 to 1:500. Epitope retrieval with citrate Buffer pH 6.0 is recommended for FFPE cell sections.

WB: 01:01,00

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1000 μg/mL

Buffer: Borate Buffered Saline (BBS) pH 8.2 with 0.09 % Sodium Azide, BSA-Free

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: 2 - 8 °C

Haltbarkeit: 12 months

Details zu ZEB1

Target: ZEB1 (Zinc Finger E-Box Binding Homeobox 1 (ZEB1))

Andere Bezeichnung: ZEB1

Hintergrund: ZEB1 (zinc-finger E-box-binding homeobox 1), also known as TCF8 (transcription factor 8), is a delta-EF1/ZFH-1 C2H2-type zinc finger that bears seven C2H2-type zinc fingers and one homeobox DNA-binding domain. ZEB1 is a transcriptional repressor of interleukin-2 (IL-2). Mutations in the ZEB1 gene are associated with posterior corneal dystrophy type 3 (PPC3) a rare disorder characterized by metaplasia and overgrowth of corneal endothelial cells. ZEB1 appears to be critical to epithelial to mesenchymal transitions (EMT) during development and cancer metastasis. As a transcription factor involved in EMT, ZEB1 promotes EMT by repressing genes associated with the epithelial phenotype and activates genes associated with the mesenchymal phenotype.

Gen-ID: 6935

UniProt: P37275

Pathways: Regulation of Muscle Cell Differentiation